RoosterVial™-hBM-XF are Human Bone-Marrow Derived Mesenchymal Stem/Stromal Cells (hBM-MSCs) isolated from adult human iliac crest from a variety of normal, healthy donors and expanded to a population doubling level (PDL) of 6-10, post-mononuclear cell isolation. Available in both 1M or high-volume 10M cell per vial formats to meet your needs throughout product development.
Each lot is release tested to expand >10-fold within 4 to 6 days in a media exchange free process when paired with RoosterNourishTM-MSC-XF bioprocess medium and conforms to ISCT minimal criteria for hMSC identity including cell surface marker expression and tri-lineage differentiation potential, expansion potential, and sterility. Accompanying QC brief contains industry-leading functional characterization including immunomodulatory potential (IDO assay) and angiogenic cytokine secretion, giving added confidence in quality, reproducibility, and ease of integration.
Designed for robust, reproducible, standardized scale-up and supported by our media exchange free 2D and 3D bioreactor processes and RoosterNourish™-MSC-XF expansion media, RoosterVial™-hBM-XF can efficiently and reproducibly get you the millions or billions of hMSCs to accelerate your Research and Product Development.
Product Features
1M (MSC-031) or 10M (MSC-030) cryopreserved, XF hBM-MSCs with multiple available donors
Supplied, easy-to-follow expansion protocols, saving you months of process development time.
Supported by 1st in class hMSC identity and functional characterization
> 10-fold, media exchange free expansion in 4 to 5 days when cultured with RoosterNourishTM-MSC-XF
RoosterVial™-hBM-XF (MSC-030/MSC-031) cultured in RoosterNourish™-MSC-XF (KT-016) have a fibroblastic cell morphology (left) and express hMSC cell surface markers (right).
Immunomodulatory activity (left, IDO activity increase in response to IFNy) and angiogenic cytokine secretion of a representative RoosterVial™-hBM-XF (MSC-030/MSC-031) lot (right).
Trilineage differentiation of a representative RoosterVial™-hBM-XF (MSC-030/MSC-031) lot. Adipogenesis, left; Osteogenesis, middle; Chondrogenesis, right.
