MSC 2015is quickly approaching next month and we at RoosterBio are getting ready. This conference is arguably the single most important conference related to MSCs, and Cleveland is the considered by many to be the birthplace of the current paradigm of MSCs used in therapeutic contexts. We will be sending most of our company, and we do look forward to seeing everyone there. Not only is this...
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RoosterBio participated in the annual Tissue Engineering and Regenerative Medicine International Society’s Annual Meeting of the Americas chapter (or TERMIS-AM for short) in Dec 2014. You can find a lot of content on the meeting at the conference website where you can download the program for free, as well as read the published abstracts in the journal Tissue Engineering. The final registration...
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Human MSCs are the single most used cell source for tissue engineering and regenerative medicine applications, and clinical trials involving hMSCs have outpaced all other cell types in recent years (see hereand here). However, despite indications of clinical effectiveness (see here and here), there is repeated news of the failure of high-profile MSC trials to demonstrate efficacy in a number of...
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MSCs truly are the Workhorse of Regenerative Medicine, and their use in Orthopaedic applications is where clinical translation was initially imagined. However, the robust signaling activityof MSCs has widened the range of clinical indications to include cardiac, vascular, and neurological regeneration, as well as immunological applications (eg. GVHD, Chron’s disease), and more recently, cancer...
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Extreme cellular stress can trigger senescence, a mechanism protecting
against malignant cell transformation.
Adapted from:
Kovacic J C et al. Circulation. 2011;123:1650-1660
We’ve mentioned several times on this blog how standardizationof materials, equipment and processes is critical to driving reproducibility and robustness of living cell technologies. As we continue to engage researchers in...
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@JennWebb recently wrote an article for the O’Reilly Radar titled Democratizing Technology and the Road to Empowerment. She starts out the article with a nice summary of what it means to Democratize Technology. Jenn writes “Advancements in technology are making what once was relegated only to highly educated scientists, engineers and developers accessible to — and affordable for — the...
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