Developed to overcome downstream process-related particle loss, AgentV™-DSP solves key DSP challenges and increases particle yields up to 10-fold over legacy solutions.
Biological components in conditioned media are a consistent problem during downstream processing of exosomes and extracellular vesicles. These components block filters and lead to significant EV loss at every processing step.
AgentV™-DSP, a downstream processing treatment that contains recombinant biological molecules, solves DSP filtration problems by preventing filter fouling. By doing so, it provides novel processing advantages such as: enabling the use of smaller cutoff filters, enabling greater filter loading capacity, and enabling greater EV yield through filtration. These advantages lead to a 40-70% particle recovery through DSP resulting in an up to 10-fold increase in particle yield.
Use AgentV™-DSP as part of RoosterCollect™ systems or potentially as part of any system that experiences aggregate- or biomaterial-related filtration issues.
