hMSC & Exosome Bioreactor Kits

Overview

RoosterBio’s Exosome Production Bioreactor Kits are all-in-one cell and media systems to support 3D and perfusion bioreactor production of MSC exosomes/EVs from seed-train through bioreactor production and collection.

Kits are available for bone marrow (BM), umbilical cord (UC), or adipose (AD)-derived exosomes and include the required xeno-free (XF) hMSCs, RoosterNourish expansion media, RoosterReplenish bioreactor feed, and RoosterCollect collection media to follow our step-by-step process recommendations.

No matter the level of bioreactor experience, implement a process that leverages the industry’s most productive exosome production system.

Intended Use: Research Use Only

Contact us for information on GMP MSC exosome production.

Product Features

• Xeno-Free | GMP formats available
• A media exchange-free process vetted in multiple platforms*
• Enables 3D exosome manufacturing from 100ml through >50L
  • 500 ml kit protocols for:
    • 4 x 125ml Spinner Flask EV Protocol
    • 4 x PBS Biotech 0.1L Mini EV Protocol
    • 1 x PBS Biotech 0.5L Mini EV Protocol
    • 2 x Sartorius AMBR250 EV Protocol
  • 3L Kits for Eppendorf, PBS Biotech, and other platforms
    • Contact us for larger scale (from 3L to >50L) protocols

*Our system has been vetted in multiple bioreactor platforms, including PBS, Sartorius, Pall, Eppendorf, Univercells Scale-X, Terumo BCT hollow-fiber, OmniBRx CellBRx, Corning AscentFBR, and others.  Please contact us at info@roosterbio.com for platform specific recommendations.

Microcarriers not included:  Per our protocols and process recommendations for bioreactor cell culture, RoosterBio suggests using either Corning® Low Concentration Synthemax® II Microcarriers (3781) or Sartorius SoloHill Collagen-coated APC Microcarriers (C/CIR-221).