Xeno-free umbilical cord-derived hMSCs and expansion media

  • SKU/Catalog No: K40105
  • Components: C43001UC; SU-022; SU-016
  • Unit Size: 1 x 1M cryopreserved cells and 1 x 500mL RoosterNourish-MSC-XF (bioprocess medium, including 1 x 10mL of RoosterBooster™-MSC-XF)
  • Price: $1,234.00
Designed to enable rapid testing of a translation-friendly umbilical cord derived MSC system.
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The RoosterKit™-hUC-1M-XF contains 1 vial of 1M cryopreserved hUC-MSCs (C43001UC, RoosterVial™-hUC-1M-XF) and 500 mL of RoosterNourish™-MSC-XF (KT-016) bioprocess media. When used alongside supplied RoosterBio® expansion protocols this kit can generate >500M cells in 10 days.

RoosterBio’s xeno-free (XF) hUC-MSCs, isolated from the perivascular Wharton’s Jelly region of the human umbilical cord and manufactured with cGMP compatible processes, contain >1M viable xeno-free hMSCs from a single healthy donor. Each produced lot is released based on hMSC identity (cell surface marker expression), expansion potential, sterility, and differentiation potential and provided QC brief contains industry-leading functional characterization (immunomodulatory potential (IDO assay), angiogenic cytokine secretion), giving added confidence in quality, reproducibility, and ease of integration. It is ideal for small scale testing and optimization of experimental conditions for future scale-up and manufactured with cGMP compatible processes providing a direct path to translation.

Designed to meet the quality and volume needs of today’s product developers and translationally focused researchers.

RoosterVial-hUC-XF manufactured and sold by RoosterBio, INC and supported by licensed technology from Tissue Regeneration Therapeutics Inc. (TRT) core technology and patent family: US 8,790,923; US 8,278,102; US 7,547,546; US 9,611,456; US 9,611,456; US 8,481,311; US 9,611,456. Access fees and license opportunities may apply.

Intended Use: Research Use Only

Product Features

  • 1M cryopreserved XF hUC-MSCs & 1 RoosterNourish-MSC-XF medium (KT-016)
  • Supplied, easy-to-follow expansion protocols for rapid testing and optimization
  • > 20 fold expansion in 4 to 5 days
  • Built-in batch culture manufacturing process capable of generating > 500 M cells in 8 to 10 days
  • Multiple donors available for screening
  • Manufactured with the same cGMP compatible processes as 10M vial (C43002UC)
  • 1st in class CofA and QC Brief with lot-specific functional hMSC characterization (identity, trilineage differentiation, immunomodulatory potential, and angiogenic cytokine secretion)
RoosterVial™-hUC-1M-XF (xeno-free, C43001UC) cultured in RoosterNourish™-MSC-XF (KT-016) have a fibroblastic cell morphology (left) and express hMSC cell surface markers (right).
Immunomodulatory activity (left, IDO activity increase in response to IFN-y) and angiogenic cytokine secretion (right) of a representative RoosterVial™-hUC-1M-XF (C43001UC) lot.
Trilineage differentiation of a representative RoosterVial™-hUC-1M-XF (C43001UC) cell lot. Adipogenesis, left; Osteogenesis, middle (macro and 100x, for Ca2+ deposition); Chondrogenesis, right.
Product Documentation

Protocols and Information

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