RoosterVial™-hAD-XF are Human Adipose Derived Mesenchymal Stem/Stromal Cells (hAD-MSCs) isolated from adult human adipose from a variety of normal, healthy donors and expanded to a population doubling level (PDL) of 6-10, post-mononuclear cell isolation. Available in both 1M or high-volume 10M cell per vial formats to meet your needs throughout product development.
Each lot is release tested to expand >10-fold within 4 to 6 days in a media exchange free process when paired with RoosterNourishTM-MSC-XF bioprocess medium and conforms to ISCT minimal criteria for hMSC identity including cell surface marker expression and tri-lineage differentiation potential, expansion potential, and sterility. Accompanying QC brief contains industry-leading functional characterization including immunomodulatory potential (IDO assay) and angiogenic cytokine secretion, giving added confidence in quality, reproducibility, and ease of integration.
Designed for robust, reproducible, standardized scale-up and supported by our media exchange free 2D and 3D bioreactor processes and RoosterNourish™-MSC-XF expansion media, RoosterVial™-hAD-XF can efficiently and reproducibly get you the millions or billions of hMSCs to accelerate your Research and Product Development.
Product Features
1M (C46001AD) or 10M (C46010AD) cryopreserved, XF hAD-MSCs with multiple available donors
Supplied, easy-to-follow expansion protocols, saving you months of process development time.
Supported by 1st in class hMSC identity and functional characterization
> 10-fold, media exchange free expansion in 4 to 5 days when cultured with RoosterNourishTM-MSC-XF
XF RoosterVial-hAD (xeno-free, C46001AD/C46010AD) cultured in RoosterNourish-MSC-XF (KT-016) expansion profile (left) and hMSC specific cell surface marker expression (right) after 2 passages.
Angiogenic cytokine secretion (left) and immunomodulatory activity (right, IDO activity increase in response to IFNy) of a representative XF RoosterVial-hAD (C46001AD/C46010AD).
Trilineage differentiation of a representative XF RoosterVial-hAD (C46001AD/C46010AD) lot. Osteogenesis, left; Adipogenesis, middle; Chondrogenesis, right.
