RoosterVial™-hUC-XF are Human Umbilical Cord Derived Mesenchymal Stem/Stromal Cells (hUC-MSCs) isolated from the perivascular Wharton’s Jelly region of the human umbilical cord and expanded to a population doubling level (PDL) of 6-10, post-mononuclear cell isolation. Available in both 1M or high-volume 10M cell per vial formats to meet your needs throughout product development.
Each lot is release tested to expand >10-fold within 4 to 6 days in a media exchange free process when paired with RoosterNourishTM-MSC-XF bioprocess medium and conforms to ISCT minimal criteria for hMSC identity including cell surface marker expression and tri-lineage differentiation potential, expansion potential, and sterility. Accompanying QC brief contains industry-leading functional characterization including immunomodulatory potential (IDO assay) and angiogenic cytokine secretion, giving added confidence in quality, reproducibility, and ease of integration.
Designed for robust, reproducible, standardized XF scale-up and supported by our media exchange free 2D and 3D bioreactor processes and RoosterNourish™-MSC-XF expansion media, XF RoosterVial™-hUC can efficiently and reproducibly get you the millions or billions of hMSCs to accelerate your Research and Product Development.
*RoosterVial-hUC-XF manufactured and sold by RoosterBio, INC and supported by licensed technology from Tissue Regeneration Therapeutics Inc. (TRT) core technology and patent family: US 8,790,923; US 8,278,102; US 7,547,546; US 9,611,456; US 9,611,456; US 8,481,311; US 9,611,456.
XF RoosterVial™-hUC (xeno-free, C43001UC/C43002UC) cultured in RoosterNourish™-MSC-XF (KT-016) expansion profile (left) have a fibroblastic cell morphology (right).
hMSC specific cell surface marker expression (left), Immunomodulatory activity (center, IDO activity increase in response to IFNy) and angiogenic cytokine secretion of a representative XF RoosterVial™-hUC (C43001UC/C43002UC) lot (right).
Trilineage differentiation of a representative XF RoosterVial™-hUC (C43001UC/C43002UC) lot. Adipogenesis, left; Osteogenesis, middle; Chondrogenesis, right.
