To meet growing demand, economical biomanufacturing processes are needed to produce sufficient hMSCs and exosomes. RoosterBio has developed a xeno-free, scalable hMSC bioreactor process that maintains critical quality attributes, which can be implemented in PBS Biotech’s Vertical-Wheel® Bioreactor platform for a uniform, low-shear environment. This application note covers details on the methods, results, and key considerations when using this joint process and platform.