The XF hUC-MSC Donor Screening Kit contains 3 vials of 1M cryopreserved xeno-free (XF) cells from three (3) selected donors (RoosterVial™-hUC-1M-XF, C43001UC) and 500 mL of RoosterNourish™-MSC-XF (K82016). RoosterVial™-hUC-1M-XF are Xeno-free Human Umbilical Cord Derived Mesenchymal Stem/Stromal Cells (hUC-MSCs) isolated from the perivascular Wharton’s Jelly region of the human umbilical cord. RoosterNourish™- MSC-XF is an affordable, highly-productive XF bioprocess medium for the rapid expansion of human mesenchymal stem/stromal cells (hMSCs) from multiple tissue sources. All RoosterBio® XF hUC-MSCs meet the ISCT minimal criteria for defining MSCs including surface protein expression and trilineage differentiation potential. The product vial undergoes stringent safety and sterility testing and is backed by a lot-specific CoA. Additionally, RoosterVial™-hUC-1M-XF has industry-leading functional characterization, including immunomodulatory potential and angiogenic cytokine secretion profiling included in the accompanying QC Brief and detailed per lot.
Allows cell and non-cell experts to rapidly and economically screen multiple (3) donors for experiments and product development and to evaluate effects of donor variability on your product or process. Scale confidently with data driven selection of XF hUC-MSCs using a translation-friendly system which has supported top regenerative medicine research, product developers, and translational institutions.
Designed to meet the quality and volume needs of today’s product developers and translationally focused researchers.
*RoosterVial-hUC-XF manufactured and sold by RoosterBio, INC and supported by licensed technology from Tissue Regeneration Therapeutics Inc. (TRT) core technology and patent family: US 8,790,923; US 8,278,102; US 7,547,546; US 9,611,456; US 9,611,456; US 8,481,311; US 9,611,456.
Intended Use: Research Use Only
Product Features
3 vials of 1M cryopreserved XF hUC-MSCs; each from a different donor
1 RoosterNourish™-MSC-XF with accompanying expansion protocols to rapidly expand donors for side-by-side comparisons
Each vial generates > 20M cells within 7 days when cultured with RoosterNourish™-MSC-XF
Select donors from our “Donor Grid” based on donor attributes or functional characteristics
Scale up with RoosterVial™-hUC-10M-XF after donor comparison
Industry-leading hMSC identity and functional characterization
All lots of RoosterVial™-hUC-1M-XF (C43001UC) cultured in RoosterNourish™-MSC-XF have a fibroblastic cell morphology (left). Consistent expression of hMSC cell surface markers in multiple RoosterVial™-hUC-1M-XF cell lots (right).
Donor-to-donor variation in multiple lots of RoosterVial™-hUC-1M-XF (C43001UC). Immunomodulatory activity (left, IDO activity increase in response to IFNy). Angiogenic cytokine secretion (right). Values are normalized (%) to the average activity/secretion values of the plotted lots.
Trilineage differentiation of a representative RoosterVial™-hUC-1M-XF (C43001UC) cell lot. Adipogenesis, left; Osteogenesis, middle (macro and 100x, for Ca2+ deposition); Chondrogenesis, right.
