Above, diagram of the hypothesized role of MSCs to disrupt the cycle of neutrophil “NETosis” in COVID-19 lung damage, via its immunomodulatory paracrine activity on Tregs and macrophages. Could human ... More
This year’s ISCT conference had a different look than in years past, as the organizers quickly pivoted from planning a conference in Paris to a fully virtual event due to ... More
Human Mesenchymal Stem Cells or Mesenchymal Stromal Cells, the “workhorse” of Regenerative Medicine (RegenMed), are a critical starting material in a growing variety of established and emerging RegenMed products. [1],[2] ... More
How hMSCs Could Work in Patients, What Are Their Biomanufacturing Needs, and When Can They Be Safely Stockpiled? On New Year’s Day, 2020, buried in the headlines was news of a ... More
On May 1st, thought leaders from the ISEV and ISCT published online in Cytotherapy a joint statement, “ISEV and ISCT statement on EVs from MSCs and other cells: considerations for potential ... More
Where are we now in our therapeutic response to COVID? As of writing this article, over 1.5 Million Americans have confirmed cases of COVID-19 and 90,000 lives have been lost. ... More
Amid the global search for treatments for COVID-19 related lung disorders, MSCs emerged as one of the promising solutions to treat Acute Respiratory Distress Syndrome (ARDS) [1, 2]. (See our ... More
Patient Safety as First Priority in COVID-19 Treatment The medical and scientific communities are ardently working on promising new treatments for COVID-19. With the urgency to treat patients currently affected ... More
Industry sponsored MSC-based clinical trial activities for COVID-19 As of this writing, more than a dozen companies and groups have announced their interests to develop mesenchymal stromal/stem cell (MSC) based ... More
“If you can’t fly then run, if you can’t run then walk, if you can’t walk then crawl, but whatever you do you have to keep moving forward.” ― Martin ... More