The XF hBM-MSC Donor Screening Kit contains 3 vials of 1M cryopreserved xeno-free (XF) cells from three (3) selected donors (RoosterVial™-hBM-1M-XF, MSC-031) and 500 mL of RoosterNourish™-MSC-XF (K82016). RoosterVial™-hBM-1M-XF are Xeno-free Human Bone-Marrow Derived Mesenchymal Stem/Stromal Cells (hBM-MSCs) isolated from normal healthy adult donors. RoosterNourish™- MSC-XF is an affordable, highly-productive XF bioprocess medium for the rapid expansion of human mesenchymal stem/stromal cells (hMSCs) from multiple tissue sources. All RoosterBio® XF hBM-MSCs meet the ISCT minimal criteria for defining MSCs including surface protein expression and tri-lineage differentiation potential. The product vial undergoes stringent safety and sterility testing and is backed by a lot-specific CoA. Additionally, RoosterVial™-hBM-1M-XF has industry-leading functional characterization, including immunomodulatory potential and angiogenic cytokine secretion profiling included in the accompanying QC Brief and is detailed per lot.
Designed to allow cell and non-cell experts to rapidly and economically screen multiple (3) donors for experiments and product development and to evaluate effects of donor variability on your product or process. Scale confidently with data driven selection of XF hBM-MSCs using a translation-friendly system which has supported top regenerative medicine research, product developers, and translational institutions in over 25 countries.
Product Features
3 vials of 1M cryopreserved XF hBM-MSCs; each from a different donor
1 RoosterNourish™-MSC-XF with accompanying expansion protocols to rapidly expand donors for side-by-side comparisons
Each vial generates > 10M cells within 7 days when cultured with RoosterNourish™-MSC-XF
Select donors from our “Donor Grid” based on donor attributes or functional characteristics
Scale up with RoosterVial™-hBM10M-XF after donor comparison
Industry-leading hMSC identity and functional characterization
Intended Use: Research Use Only
All lots of RoosterVial™-hBM-1M-XF (MSC-031) cultured in RoosterNourish™-MSC-XF have a fibroblastic cell morphology (left). Consistent expression of hMSC cell surface markers in multiple RoosterVial™-hBM-1M-XF cell lots (right).
Donor-to-donor variation in multiple lots of RoosterVial™-hBM-1M-XF (MSC-31). Immunomodulatory activity (left, IDO activity increase in response to IFNy). Angiogenic cytokine secretion (right). Values are normalized (%) to the average activity/secretion values of the plotted lots.
Trilineage differentiation of a representative RoosterVial™-hBM-1M-XF (MSC-031) lot. Adipogenesis, left; Osteogenesis, middle; Chondrogenesis, right.
