Above, diagram of the hypothesized role of MSCs to disrupt the cycle of neutrophil “NETosis” in COVID-19 lung damage, via its immunomodulatory paracrine activity on Tregs and macrophages. Could human ... More
How hMSCs Could Work in Patients, What Are Their Biomanufacturing Needs, and When Can They Be Safely Stockpiled? On New Year’s Day, 2020, buried in the headlines was news of a ... More
On May 1st, thought leaders from the ISEV and ISCT published online in Cytotherapy a joint statement, “ISEV and ISCT statement on EVs from MSCs and other cells: considerations for potential ... More
Where are we now in our therapeutic response to COVID? As of writing this article, over 1.5 Million Americans have confirmed cases of COVID-19 and 90,000 lives have been lost. ... More
Industry sponsored MSC-based clinical trial activities for COVID-19 As of this writing, more than a dozen companies and groups have announced their interests to develop mesenchymal stromal/stem cell (MSC) based ... More
“If you can’t fly then run, if you can’t run then walk, if you can’t walk then crawl, but whatever you do you have to keep moving forward.” ― Martin ... More
Authored by Mayasari Lim, PhD, Jonathan Carson, PhD, and Jon A. Rowley, PhD, RoosterBio, Inc. Some research suggests that ARDS might be treatable with the secretome of MSCs. Scientists and ... More
With acknowledgement to scientists who sounded the alarm like Dr. Liz Specht and to all health workers on the front lines. What a Successful MSC or MSC-EV Therapy Would Mean ... More
Amidst the scramble and panic-buying that some of us are experiencing, several treatments to combat this novel coronavirus (COVID-19) are underway. As of this writing, there are 66 clinical trials ... More
Authored by: Jon Carson, Iain Farrance, John Getz, and Jon A. Rowley, RoosterBio, Inc. On 31-December-2019, Chinese officials alerted the World Health Organization of an outbreak of pneumonia cases in ... More