Xeno-Free Human Bone Marrow-Derived MSCs

  • SKU/Catalog No: MSC-030-OLD
  • Components: N/A
  • Unit Size: 1 x 10 million xeno-free (XF) cryopreserved cells
  • Price: $2,580.00
Designed for product developers and translational researchers needing quick access to billions, not millions, of hMSCs.
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RoosterVial™-hBM-10M-XF are Human Bone-Marrow Derived Mesenchymal Stem/Stromal Cells (hBM-MSCs) isolated from normal healthy adult donors under xeno-free (XF) conditions. This novel high-volume format contains >10M cryopreserved XF hBM-MSCs guaranteed to generate >100M cells within 7 days when paired with RoosterNourishTM-MSC-XF bioprocess medium. Our XF hBM-MSCs are isolated from adult human iliac crest and expanded from a variety of normal, healthy donors to a population doubling level (PDL) of 6-10, post-mononuclear cell isolation. Each produced lot is released based on ISCT minimal criteria for hMSC identity including cell surface marker expression and tri-lineage differentiation potential, expansion potential, and sterility. Accompanying QC brief contains industry-leading functional characterization including immunomodulatory potential (IDO assay) and angiogenic cytokine secretion, giving added confidence in quality, reproducibility, and east of integration. Designed for robust, reproducible, standardized XF scale-up and supported by our 2D and our 3D bioreactor processes. RoosterVial™-hBM-10M-XF can efficiently get you to billions of hMSCs to “Radically Simplify” your Research and Product Development.

A research version and precursor to our cGMP RoosterVial™-hBM , RoosterBio® XF-hBM-MSCs are offered in 5 or 10 vial working cell banks of 10M cells per vial for future scale-up along with lots manufactured concurrently – for small scale optimization available in 1M hMSC RoosterKit™-hBM-1M-XF

Product Features

  • 10M cryopreserved, xeno-free hBM-MSCs
  • Supplied, easy-to-follow expansion protocols, saving you months of process development time.
  • Manufactured with scalable processes and cryopreserved using standard, controlled processes
  • Supported by 1st in class hMSC identity and functional characterization
  • Generate 100M cells within 7 days and 1B cells in two weeks or less when cultured with RoosterNourish™-MSC-XF

Intended Use: Research Use Only

RoosterVial™-hBM-10M-XF (xeno-free, MSC-030) cultured in RoosterNourish™-MSC-XF (KT-016) have a fibroblastic cell morphology (left) and express hMSC cell surface markers (right).
Immunomodulatory activity (left, IDO activity increase in response to IFNy) and angiogenic cytokine secretion of a representative RoosterVial™-hBM-10M-XF (MSC-030) lot (right).
Trilineage differentiation of RoosterVial™-hBM-10M-XF (MSC-030) of a representative RoosterVial™-hBM-10M-XF (MSC-030) lot. Adipogenesis, left; Osteogenesis, middle; Chondrogenesis, right.
Product Documentation

Protocols and Information

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